Original Research Article

The purpose of an Original Research Article is to present the research, together with its original findings and data, that the author has conducted themselves or has had a significant contribution in acquiring the data. Original Research Articles are considered a primary source. The authors aim to answer a research question by employing suitable methods and discussing their results within their hypothesis and the broader scientific context of their field. As such, an Original Research Article must include an introduction, a methods section, the results of the research, and a discussion.

Systematic Review

Systematic reviews comprise critical information based on published studies pertaining aetiology, diagnostic and therapeutic approaches, as well as prevention or prognosis towards/of a given clinical entity. In order to provide an evidence-based review on a focused topic please follow EQUATOR Reporting Guidelines. The authors aim to answer a research question by identifying relevant works, assessing their quality, summarizing the evidence and interpreting the results. As such, a Systematic Review must include an abstract, an introduction, a methods section, the results of the research, and a discussion.

Research Letter

Research letter is a concise report of original research, which not exceed 1000 words of text and may include 2 figures or tables maximum. Letters must not duplicate other materials previously published or submitted for publishing. Research letter must include Introduction, Methods, Results and Discussion. Online supplementary material is only allowed for absolutely necessary methods description but not additional results or discussion.

Case Report

Case reports presents a case study with new insight or unusual noteworthy course. Case reports should follow CARE Reporting Guidelines. Publication of any personal information about an identifiable living patient requires the explicit consent of the patient or guardian. As such Case Report must include an abstract, an introduction, a case presentation and a discussion section.

Guidelines

The submitted manuscript should follow the structure described below:

1. Abstract

   The Abstract of your article should give a brief overview of the context and state the research question you attempt to answer. It should provide a concise summary of your results, highlight your key findings, and communicate their implication. Unless of relevance, details on methods can be omitted. Do not use any references or abbreviations in your abstract.

2. Introduction

   The introduction should include a short literature review explaining the background of your study and clearly state the primary aim and objectives of the research presented. Specify how your research aims to fill in any current gaps in your field.

3. Methods 
   1. Original research article

      The methods section should describe the study design and setting relevant for appreciation, interpretation, and replication of the data. Include all techniques and procedures employed to gather any of the data presented in the results section of your article. Mention all materials and apparatus used with their generic names. If you use propriety brand names, put these in brackets after the generic name. Specify which statistical analysis you have used. You may include figures of the procedure as a visual aid for better comprehension, especially regarding uncommon methods or those you have established yourself as part of your experimental setup.

   2. Systematic review

      The methodological section should mainly be focused on the workflow of data search within the most relevant databases e.g. MEDLINE/PubMEd, Cochrane, Embase, CINAHL etc. The literature search has to be based on the PRISMA-protocol (https://www.equator-network.org/reporting-guidelines/prisma/). Further, is it required to present the most up to date literature found, i.e. primary literature search has to be carried out within 1 months upon paper upload. Please, report all search terms or operators used when conducting the search, describe publication years or language limitations, your inclusion and exclusion criteria, as well as quality rating systems employed. Publications with the highest evidence level should be assessed with an excessive emphasis.

4. Results
   1. Original research article

      Present all relevant data that you have gathered from your research in the form of text, figures, and tables, that have been essential to answer your research question. Include legends in your figures and tables. Present the result of your statistical analysis as well.

   2. Systemic review

      Present all relevant data that you have gathered from your literature search in the form of text, PRISMA-flowchart figure, assess the evidence with the e.g. GRADE quality rating system, add further figures, and tables, that have been essential to answer your research question or describe the results. Include legends in your figures and tables.

5. Discussion

   Use this section to discuss your results and how they can be interpreted regarding your research question. Results should also be put into perspective within the broader scientific context of your field and related to the background information and literature review that has been mentioned in the introduction part. You may want to state the implication of your results and their limitations and conclude with an outlook for future directions.

6. Acknowledgements

   Please acknowledge contributions that do not meet the criteria for authorship. Include technical and financial support, which can be inside or outside of your institute.

7. Author contributions

   Each author is expected to have made substantial contribution to the work and has approved the submitted version. Please be aware, that the corresponding author will be the main contact during submission process.

8. Declarations and Conflict of Interest

   Authors must declare all interests that could be preserved as conflicting and state how the research and publication was funded. For more information on ethical considerations, please see “requirements”.

9. References

   All references from any type of source have to be cited. A list of detailed list of references has to be attached to the final section of your article.